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Ribosomal DNA copy number loss and sequence variation in cancer
Ribosomal DNA is one of the most variable regions in the human genome with respect to copy number. Despite the importance of rDNA for cellular function, we know virtually nothing about what governs its copy number, stability, and sequence in the mammalian genome due to challenges associated with map...
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480814/ https://ncbi.nlm.nih.gov/pubmed/28640831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006771 |
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