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An Untargeted Proteomics and Systems-based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells

The anti-malarial drug artesunate is a semi-synthetic derivative of artemisinin, the principal active component of a medicinal plant Artemisia annua. It is hypothesized to attenuate allergic asthma via inhibition of multiple signaling pathways. We used a comprehensive approach to elucidate the mecha...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Ravindra, Kodihalli C., Ho, Wanxing Eugene, Cheng, Chang, Godoy, Luiz C., Wishnok, John S., Ong, Choon Nam, Wong, W.S. Fred, Wogan, Gerald N., Tannenbaum, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480315/
https://ncbi.nlm.nih.gov/pubmed/26340163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00105
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