M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer

Reprogramming of glucose metabolism in tumor cells is referred to as the Warburg effect and results in increased lactic acid secretion into the tumor microenvironment. We have previously shown that lactic acid has important roles as a pro‐inflammatory and immunosuppressive mediator and promotes tumo...

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Dettagli Bibliografici
Pubblicato in:Cancer Sci
Autori principali: Ohashi, Toshimitsu, Aoki, Mitsuhiro, Tomita, Hiroyuki, Akazawa, Takashi, Sato, Katsuya, Kuze, Bunya, Mizuta, Keisuke, Hara, Akira, Nagaoka, Hitoshi, Inoue, Norimitsu, Ito, Yatsuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480089/
https://ncbi.nlm.nih.gov/pubmed/28370718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13244
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