M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer

Reprogramming of glucose metabolism in tumor cells is referred to as the Warburg effect and results in increased lactic acid secretion into the tumor microenvironment. We have previously shown that lactic acid has important roles as a pro‐inflammatory and immunosuppressive mediator and promotes tumo...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ohashi, Toshimitsu, Aoki, Mitsuhiro, Tomita, Hiroyuki, Akazawa, Takashi, Sato, Katsuya, Kuze, Bunya, Mizuta, Keisuke, Hara, Akira, Nagaoka, Hitoshi, Inoue, Norimitsu, Ito, Yatsuji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480089/
https://ncbi.nlm.nih.gov/pubmed/28370718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13244
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