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M2‐like macrophage polarization in high lactic acid‐producing head and neck cancer

Reprogramming of glucose metabolism in tumor cells is referred to as the Warburg effect and results in increased lactic acid secretion into the tumor microenvironment. We have previously shown that lactic acid has important roles as a pro‐inflammatory and immunosuppressive mediator and promotes tumo...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Ohashi, Toshimitsu, Aoki, Mitsuhiro, Tomita, Hiroyuki, Akazawa, Takashi, Sato, Katsuya, Kuze, Bunya, Mizuta, Keisuke, Hara, Akira, Nagaoka, Hitoshi, Inoue, Norimitsu, Ito, Yatsuji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480089/
https://ncbi.nlm.nih.gov/pubmed/28370718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13244
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