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Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway

Talin1 is an adaptor protein that conjugates integrins to the cytoskeleton and regulates integrins and focal adhesion signaling. Several studies have found that Talin1 is overexpressed in several tumor types and promotes tumor progression. However, the explicit role of Talin1 in hepatocellular carci...

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Bibliografiska uppgifter
I publikationen:Cancer Sci
Huvudupphovsmän: Chen, Peijuan, Lei, Ling, Wang, Jian, Zou, Xuejing, Zhang, Dongyan, Deng, Ling, Wu, Dehua
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480078/
https://ncbi.nlm.nih.gov/pubmed/28375585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13247
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