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Downregulation of Talin1 promotes hepatocellular carcinoma progression through activation of the ERK1/2 pathway

Talin1 is an adaptor protein that conjugates integrins to the cytoskeleton and regulates integrins and focal adhesion signaling. Several studies have found that Talin1 is overexpressed in several tumor types and promotes tumor progression. However, the explicit role of Talin1 in hepatocellular carci...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Chen, Peijuan, Lei, Ling, Wang, Jian, Zou, Xuejing, Zhang, Dongyan, Deng, Ling, Wu, Dehua
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480078/
https://ncbi.nlm.nih.gov/pubmed/28375585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13247
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