Control of Mitochondrial Transcription Specificity Factors (TFB1M and TFB2M) by Nuclear Respiratory Factors (NRF-1 and NRF-2) and PGC-1 Family Coactivators

In vertebrates, mitochondrial DNA (mtDNA) transcription is initiated bidirectionally from closely spaced promoters, HSP and LSP, within the D-loop regulatory region. Early studies demonstrated that mtDNA transcription requires mitochondrial RNA polymerase and Tfam, a DNA binding stimulatory factor t...

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Publicado en:Mol Cell Biol
Autores principales: Gleyzer, Natalie, Vercauteren, Kristel, Scarpulla, Richard C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2005
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548005/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15684387/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.4.1354-1366.2005
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