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Activation of a PGC-1-related Coactivator (PRC)-dependent Inflammatory Stress Program Linked to Apoptosis and Premature Senescence

PGC-1-related coactivator (PRC), a growth-regulated member of the PGC-1 coactivator family, contributes to the expression of the mitochondrial respiratory apparatus. PRC also orchestrates a robust response to metabolic stress by promoting the expression of multiple genes specifying inflammation, pro...

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Autors principals: Gleyzer, Natalie, Scarpulla, Richard C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605620/
https://ncbi.nlm.nih.gov/pubmed/23364789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.426841
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