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Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia

The NLRP3 inflammasome has been reported to be activated by atherogenic factors, whereby endothelial injury and consequent atherosclerotic lesions are triggered in the arterial wall. However, the mechanisms activating and regulating NLRP3 inflammasomes remain poorly understood. The present study tes...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Koka, Saisudha, Xia, Min, Chen, Yang, Bhat, Owais M., Yuan, Xinxu, Boini, Krishna M., Li, Pin-Lan
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479959/
https://ncbi.nlm.nih.gov/pubmed/28633109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.06.004
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