Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of Ondansetron and Tropisetron

5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonists are used in the prevention of chemotherapy- induced, radiation-induced and postoperative nausea and vomiting. CYP2D6 polymorphisms can influence the metabolism of some of these drugs (i.e. ondansetron and tropisetron) thereby affecting drug e...

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Bibliographic Details
Published in:Clin Pharmacol Ther
Main Authors: Bell, Gillian C., Caudle, Kelly E., Whirl-Carrillo, Michelle, Gordon, Ronald J., Hikino, Keiko, Prows, Cynthia A., Gaedigk, Andrea, Agundez, Jose A.G., Sadhasivam, Senthilkumar, Klein, Teri E., Schwab, Matthias
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479760/
https://ncbi.nlm.nih.gov/pubmed/28002639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.598
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