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The spectrum of somatic mutations in high-risk acute myeloid leukemia with -7/del(7q)

-7/del(7q) occurs in half of myeloid malignancies with adverse-risk cytogenetic features and is associated with poor survival. We identified the spectrum of mutations that co-occur with ‒7/del(7q) in forty patients with de novo or therapy-related myeloid neoplasms. -7/del(7q) leukemias have a distin...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: McNerney, Megan E., Brown, Christopher D., Peterson, April L., Banerjee, Mekhala, Larson, Richard A., Anastasi, John, Le Beau, Michelle M., White, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479678/
https://ncbi.nlm.nih.gov/pubmed/24931631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12964
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