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Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors
Iron overload due to hemochromatosis or chronic blood transfusions has been associated with the development of osteoporosis. However, the impact of changes in iron homeostasis on osteoblast functions and the underlying mechanisms are poorly defined. Since Wnt signaling is a critical regulator of bon...
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| Pubblicato in: | Haematologica |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ferrata Storti Foundation
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5479606/ https://ncbi.nlm.nih.gov/pubmed/27540134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.144808 |
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