The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing

Ebola virus and Marburg virus are members of the Filovirdae family and causative agents of hemorrhagic fever with high fatality rates in humans. Filovirus virulence is partially attributed to the VP35 protein, a well-characterized inhibitor of the RIG-I-like receptor pathway that triggers the antivi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dilley, Kari A., Voorhies, Alexander A., Luthra, Priya, Puri, Vinita, Stockwell, Timothy B., Lorenzi, Hernan, Basler, Christopher F., Shabman, Reed S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479518/
https://ncbi.nlm.nih.gov/pubmed/28636653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178717
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