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Osteopontin is Critical for Hyperactive mTOR-Induced Tumorigenesis in Oral Squamous Cell Carcinoma

Mechanistic target of rapamycin (mTOR) plays a critical role in the development of oral squamous cell carcinoma (OSCC), but the underlying mechanisms remain poorly understood. Here we have demonstrated that the expression of osteopontin (OPN) was dramatically up-regulated in OSCC tissues and cell li...

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Detalles Bibliográficos
Publicado en:J Cancer
Main Authors: Gan, Ning, Zou, Sihai, Hang, Wenming, Yang, Deqin, Zhang, Xuemei, Yin, Yibing
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479241/
https://ncbi.nlm.nih.gov/pubmed/28638450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.18031
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