New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis

Leukotrienes are inflammatory mediators that actively participate in the inflammatory response and host defense against pathogens. However, leukotrienes also participate in chronic inflammatory diseases. 5-lipoxygenase is a key enzyme in the biosynthesis of leukotrienes and is thus a validated thera...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Boudreau, Luc H., Lassalle-Claux, Grégoire, Cormier, Marc, Blanchard, Sébastien, Doucet, Marco S., Surette, Marc E., Touaibia, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478869/
https://ncbi.nlm.nih.gov/pubmed/28680195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6904634
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