Laddar...
Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling
Cocaine, a drug of abuse, increases synaptic dopamine levels in the striatum by blocking dopamine reuptake at axon terminals. Cyclin-dependent kinase 5 (Cdk5) and its activator p35, proteins involved in phosphorylation of substrates in postmitotic neurons, have been found to be up-regulated after ch...
Sparad:
| Huvudupphovsmän: | , , , , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2005
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547862/ https://ncbi.nlm.nih.gov/pubmed/15665076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409456102 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|