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Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin

Ferroportin 1 (FPN1) is transmembrane protein involved in iron homeostasis. In the duodenum, FPN1 localizes to the basolateral surface of enterocytes where it appears to export iron out of the cell and into the portal circulation. FPN1 is also abundantly expressed in reticuloendothelial macrophages...

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Detalhes bibliográficos
Main Authors: Knutson, Mitchell D., Oukka, Mohamed, Koss, Lindsey M., Aydemir, Fikret, Wessling-Resnick, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547844/
https://ncbi.nlm.nih.gov/pubmed/15665091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409409102
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