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Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux

Copper is known to play a role in iron recycling from macrophages. To examine whether cellular copper status affects expression of the iron exporter ferroportin-1 (FPN1), J774 macrophage cells were exposed to 10–100 μM CuSO(4) for up to 20 h. Copper treatment significantly increased FPN1 mRNA in a d...

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Detalhes bibliográficos
Main Authors: Chung, Jayong, Haile, David J., Wessling-Resnick, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365684/
https://ncbi.nlm.nih.gov/pubmed/14973193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306622101
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