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Copper-induced ferroportin-1 expression in J774 macrophages is associated with increased iron efflux
Copper is known to play a role in iron recycling from macrophages. To examine whether cellular copper status affects expression of the iron exporter ferroportin-1 (FPN1), J774 macrophage cells were exposed to 10–100 μM CuSO(4) for up to 20 h. Copper treatment significantly increased FPN1 mRNA in a d...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365684/ https://ncbi.nlm.nih.gov/pubmed/14973193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306622101 |
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