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Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis

BACKGROUND: Perioperative and critically ill patients are often exposed to iron (in the form of parenteral iron administration or blood transfusion) and inflammatory stimuli, but the effects of iron loading on the inflammatory response are unclear. Recent data suggest that mitochondrial reactive oxy...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Hoeft, Konrad, Bloch, Donald B., Graw, Jan A., Malhotra, Rajeev, Ichinose, Fumito, Bagchi, Aranya
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478432/
https://ncbi.nlm.nih.gov/pubmed/28430694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001653
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