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Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis

BACKGROUND: Perioperative and critically ill patients are often exposed to iron (in the form of parenteral iron administration or blood transfusion) and inflammatory stimuli, but the effects of iron loading on the inflammatory response are unclear. Recent data suggest that mitochondrial reactive oxy...

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Vydáno v:Anesthesiology
Hlavní autoři: Hoeft, Konrad, Bloch, Donald B., Graw, Jan A., Malhotra, Rajeev, Ichinose, Fumito, Bagchi, Aranya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478432/
https://ncbi.nlm.nih.gov/pubmed/28430694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001653
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