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Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism

The molecular mechanism for priapism is not well characterized. Although the nitric oxide (NO) pathway is known to mediate penile erection under normal conditions, we hypothesized that the mechanism of priapism rests in aberrant downstream signaling of this pathway based on our previous findings tha...

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Bibliographic Details
Main Authors: Champion, Hunter C., Bivalacqua, Trinity J., Takimoto, Eiki, Kass, David A., Burnett, Arthur L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC547836/
https://ncbi.nlm.nih.gov/pubmed/15668387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407183102
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