Erythropoietin signaling regulates heme biosynthesis

Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown. Here, using zebrafish, murine, and human models,...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Chung, Jacky, Wittig, Johannes G, Ghamari, Alireza, Maeda, Manami, Dailey, Tamara A, Bergonia, Hector, Kafina, Martin D, Coughlin, Emma E, Minogue, Catherine E, Hebert, Alexander S, Li, Liangtao, Kaplan, Jerry, Lodish, Harvey F, Bauer, Daniel E, Orkin, Stuart H, Cantor, Alan B, Maeda, Takahiro, Phillips, John D, Coon, Joshua J, Pagliarini, David J, Dailey, Harry A, Paw, Barry H
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478267/
https://ncbi.nlm.nih.gov/pubmed/28553927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24767
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