Activation of the erythropoietin receptor promoter by transcription factor GATA-1.

Erythropoietin, a glycoprotein produced by the kidneys in response to anemia and hypoxia, is a major growth factor for cells of the erythroid lineage. Erythropoietin interacts with high-affinity cell surface receptors (EpoR) present on developing progenitors and is required for their survival. Previ...

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Bibliographic Details
Main Authors: Zon, L I, Youssoufian, H, Mather, C, Lodish, H F, Orkin, S H
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC52985/
https://ncbi.nlm.nih.gov/pubmed/1660143
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