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Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis

In erythroid cells, ferrous iron is imported into the mitochondrion by mitoferrin-1 (Mfrn1). Previously, we showed that Mfrn1 interacts with Abcb10 to enhance mitochondrial iron importation. Herein we have derived stable Friend mouse erythroleukemia (MEL) cell clones expressing either Mfrn1-FLAG or...

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Detalhes bibliográficos
Main Authors: Chen, Wen, Dailey, Harry A., Paw, Barry H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324294/
https://ncbi.nlm.nih.gov/pubmed/20427704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-259614
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