Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease

Hypercholesterolemia is a well-known risk factor for a wide range of diseases in developed countries. Here, we report that mice lacking functional LDLR (low density lipoprotein receptor), an animal model of human familial hypercholesterolemia, show circadian abnormalities. In free running behavioral...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Akashi, Makoto, Matsumura, Ritsuko, Matsuo, Takahiro, Kubo, Yuki, Komoda, Hiroshi, Node, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478205/
https://ncbi.nlm.nih.gov/pubmed/28499924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.034
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