Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease

Hypercholesterolemia is a well-known risk factor for a wide range of diseases in developed countries. Here, we report that mice lacking functional LDLR (low density lipoprotein receptor), an animal model of human familial hypercholesterolemia, show circadian abnormalities. In free running behavioral...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Akashi, Makoto, Matsumura, Ritsuko, Matsuo, Takahiro, Kubo, Yuki, Komoda, Hiroshi, Node, Koichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478205/
https://ncbi.nlm.nih.gov/pubmed/28499924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.034
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