Hypercholesterolemia Causes Circadian Dysfunction: A Potential Risk Factor for Cardiovascular Disease

Hypercholesterolemia is a well-known risk factor for a wide range of diseases in developed countries. Here, we report that mice lacking functional LDLR (low density lipoprotein receptor), an animal model of human familial hypercholesterolemia, show circadian abnormalities. In free running behavioral...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Akashi, Makoto, Matsumura, Ritsuko, Matsuo, Takahiro, Kubo, Yuki, Komoda, Hiroshi, Node, Koichi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478205/
https://ncbi.nlm.nih.gov/pubmed/28499924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.034
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