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A push-pull mechanism for regulating integrin function
Homomeric and heteromeric interactions between the αIIb and β3 transmembrane domains are involved in the regulation of integrin αIIbβ3 function. These domains appear to interact in the inactivated state but separate upon integrin activation. Moreover, homomeric interactions may increase the level of...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547819/ https://ncbi.nlm.nih.gov/pubmed/15671157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409334102 |
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