A push-pull mechanism for regulating integrin function

Homomeric and heteromeric interactions between the αIIb and β3 transmembrane domains are involved in the regulation of integrin αIIbβ3 function. These domains appear to interact in the inactivated state but separate upon integrin activation. Moreover, homomeric interactions may increase the level of...

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Bibliografiske detaljer
Main Authors: Li, Wei, Metcalf, Douglas G., Gorelik, Roman, Li, Renhao, Mitra, Neal, Nanda, Vikas, Law, Peter B., Lear, James D., DeGrado, William F., Bennett, Joel S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC547819/
https://ncbi.nlm.nih.gov/pubmed/15671157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409334102
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