Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

PURPOSE: In squamous cell carcinomas of the head and neck (HNSCC), the increasing incidence of oropharyngeal squamous cell carcinomas (OPSCCs) is attributable to human papillomavirus (HPV) infection. Despite commonly presenting at late stage, HPV-driven OPSCCs are associated with improved prognosis...

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Vydáno v:J Clin Oncol
Hlavní autoři: Chakravarthy, Ankur, Henderson, Stephen, Thirdborough, Stephen M., Ottensmeier, Christian H., Su, Xiaoping, Lechner, Matt, Feber, Andrew, Thomas, Gareth J., Fenton, Tim R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Clinical Oncology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477823/
https://ncbi.nlm.nih.gov/pubmed/27863190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.68.2955
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