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How to switch the motor on: RNA polymerase initiation steps at the single‐molecule level

RNA polymerase (RNAP) is the central motor of gene expression since it governs the process of transcription. In prokaryotes, this holoenzyme is formed by the RNAP core and a sigma factor. After approaching and binding the specific promoter site on the DNA, the holoenzyme‐promoter complex undergoes s...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Marchetti, M., Malinowska, A., Heller, I., Wuite, G.J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477531/
https://ncbi.nlm.nih.gov/pubmed/28470684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3183
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