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The ribosome destabilizes native and non‐native structures in a nascent multidomain protein

Correct folding is a prerequisite for the biological activity of most proteins. Folding has largely been studied using in vitro refolding assays with isolated small, robustly folding proteins. A substantial fraction of all cellular proteomes is composed of multidomain proteins that are often not ame...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Liu, Kaixian, Rehfus, Joseph E., Mattson, Elliot, Kaiser, Christian M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477528/
https://ncbi.nlm.nih.gov/pubmed/28474852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3189
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