Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma

BACKGROUND: Accumulating pre-clinical data indicate that the efficient induction of antigen-specific cytotoxic CD8+ T cells characterizing viral infections is caused by cross-priming where initially infected DCs produce an unique set of inflammatory factors that recruit and activate non-infected bys...

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Dettagli Bibliografici
Pubblicato in:J Immunother Cancer
Autori principali: Laurell, Anna, Lönnemark, Maria, Brekkan, Einar, Magnusson, Anders, Tolf, Anna, Wallgren, Anna Carin, Andersson, Bengt, Adamson, Lars, Kiessling, Rolf, Karlsson-Parra, Alex
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477104/
https://ncbi.nlm.nih.gov/pubmed/28642820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0255-0
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