Non-classical transpeptidases yield insight into new antibacterials

Bacterial survival requires an intact peptidoglycan layer, a 3-dimensional exoskeleton that encapsulates the cytoplasmic membrane. Historically, the final steps of peptidoglycan synthesis are known to be carried out by d,d-transpeptidases, enzymes that are inhibited by the β-lactams which constitute...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Chem Biol
Hlavní autoři: Kumar, Pankaj, Kaushik, Amit, Lloyd, Evan P., Li, Shao-Gang, Mattoo, Rohini, Ammerman, Nicole C., Bell, Drew T., Perryman, Alexander L., Zandi, Trevor A., Ekins, Sean, Ginell, Stephan L., Townsend, Craig A., Freundlich, Joel S., Lamichhane, Gyanu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477059/
https://ncbi.nlm.nih.gov/pubmed/27820797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2237
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky