Competing off-loading mechanisms of meropenem from an l,d-transpeptidase reduce antibiotic effectiveness

nork Zandi, Trevor A., Townsend, Craig A.
Argitaratua izan da Proc Natl Acad Sci U S A (2021)

Phylogenetic and biochemical analyses of mycobacterial L,D-transpeptidases reveal a distinct enzyme class that is preferentially acylated by meropenem.

nork Zandi, Trevor A., Marshburn, Robert L., Stateler, Paige K., Brammer Basta, Leighanne A.
Argitaratua izan da ACS Infect Dis (2019)

Non-classical transpeptidases yield insight into new antibacterials

nork Kumar, Pankaj, Kaushik, Amit, Lloyd, Evan P., Li, Shao-Gang, Mattoo, Rohini, Ammerman, Nicole C., Bell, Drew T., Perryman, Alexander L., Zandi, Trevor A., Ekins, Sean, Ginell, Stephan L., Townsend, Craig A., Freundlich, Joel S., Lamichhane, Gyanu
Argitaratua izan da Nat Chem Biol (2016)