NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

NAD(+) is a vital redox cofactor and a substrate required for activity of various enzyme families, including sirtuins and poly(ADP-ribose) polymerases. Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ratajczak, Joanna, Joffraud, Magali, Trammell, Samuel A. J., Ras, Rosa, Canela, Núria, Boutant, Marie, Kulkarni, Sameer S., Rodrigues, Marcelo, Redpath, Philip, Migaud, Marie E., Auwerx, Johan, Yanes, Oscar, Brenner, Charles, Cantó, Carles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476803/
https://ncbi.nlm.nih.gov/pubmed/27725675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13103
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