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NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
NAD(+) is a vital redox cofactor and a substrate required for activity of various enzyme families, including sirtuins and poly(ADP-ribose) polymerases. Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease,...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476803/ https://ncbi.nlm.nih.gov/pubmed/27725675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13103 |
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