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Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space

Many computational methods to predict the macromolecular targets of small organic molecules have been presented to date. Despite progress, target prediction methods still have important limitations. For example, the most accurate methods implicitly restrict their predictions to a relatively small nu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Peón, Antonio, Naulaerts, Stefan, Ballester, Pedro J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476590/
https://ncbi.nlm.nih.gov/pubmed/28630414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04264-w
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