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How Reliable Are Ligand-Centric Methods for Target Fishing?

Computational methods for Target Fishing (TF), also known as Target Prediction or Polypharmacology Prediction, can be used to discover new targets for small-molecule drugs. This may result in repositioning the drug in a new indication or improving our current understanding of its efficacy and side e...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Peón, Antonio, Dang, Cuong C., Ballester, Pedro J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830838/
https://ncbi.nlm.nih.gov/pubmed/27148522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00015
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