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Blood stage malaria disrupts humoral immunity to the pre-erythrocytic stage circumsporozoite protein
Many current malaria vaccines target the pre-erythrocytic stage of infection in the liver. However, in malaria endemic regions, increased blood stage exposure is associated with decreased vaccine efficacy, thereby challenging current vaccine efforts. We hypothesized that pre-erythrocytic humoral imm...
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| Publicado en: | Cell Rep |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476299/ https://ncbi.nlm.nih.gov/pubmed/28009289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.11.060 |
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