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An Inducible, Large-Intestine-Specific Transgenic Mouse Model for Colitis and Colitis-Induced Colon Cancer Research

BACKGROUND: Animal models are an important tool to understand intestinal biology. Our lab previously generated C57BL/6-Tg(Car1-cre)5Flt transgenic mice (CAC) with large intestine specific Cre recombinase (Cre) expression as a model to study colon health. AIMS: To expand the utility of the CAC mouse...

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Detalhes bibliográficos
Publicado no:Dig Dis Sci
Main Authors: Wang, Fa, Johnson, Robert L., Snyder, Paul W., DeSmet, Marsha L., Fleet, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476293/
https://ncbi.nlm.nih.gov/pubmed/26631394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-015-3971-7
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