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Generation of a Transgenic Mouse for Colorectal Cancer Research with Intestinal Cre-Expression Limited to the Large Intestine
Genetically modified mice have been used for colon cancer research but findings from these models are confounded by expression of cancer in multiple organs. We sought to create a transgenic mouse with Cre recombinase (Cre) expression limited to the epithelial cells of the large intestine and use thi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923672/ https://ncbi.nlm.nih.gov/pubmed/20663863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0195 |
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