Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H:quinone oxidoreductase 1 in Hepa1c1c7 cells

Silybum marianum (milk thistle) is a medicinal plant used for the treatment of various liver disorders. This study examined whether the main flavonolignans from S. marianum (i.e. silybin, silychristin, silydianin) and their 2,3-dehydro derivatives (i.e. 2,3-dehydrosilybin, 2,3-dehydrosilychristin, 2...

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Publicado en:Fitoterapia
Autores principales: Roubalová, Lenka, Dinkova-Kostova, Albena T., Biedermann, David, Křen, Vladimír, Ulrichová, Jitka, Vrba, Jiří
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476199/
https://ncbi.nlm.nih.gov/pubmed/28450126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fitote.2017.04.012
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