NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

The Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response elements pathway enables cells to survive oxidative stress conditions through regulating the expression of cytoprotective enzymes such as NAD(P)H:quinone oxidoreductase 1 (NQO1). T...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ghorab, Mostafa M, Alsaid, Mansour S, Higgins, Maureen, Dinkova-Kostova, Albena T, Shahat, Abdelaaty A, Elghazawy, Nehal H, Arafa, Reem K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982500/
https://ncbi.nlm.nih.gov/pubmed/27540279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S105423
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