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30. COMT Val158Met and MTHFR C677T Moderate Risk of Schizophrenia in Response to Childhood Trauma
Background: Childhood trauma is a risk factor in the etiology of schizophrenia. Mesolimbic dopamine sensitization has been hypothesized to be a mediating factor of childhood trauma on the risk of schizophrenia. Activity of catechol-O-methyltransferase (COMT) Val158Met increases mesolimbic dopamine s...
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| Pubblicato in: | Schizophr Bull |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475474/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.049 |
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