30. COMT Val158Met and MTHFR C677T Moderate Risk of Schizophrenia in Response to Childhood Trauma

Background: Childhood trauma is a risk factor in the etiology of schizophrenia. Mesolimbic dopamine sensitization has been hypothesized to be a mediating factor of childhood trauma on the risk of schizophrenia. Activity of catechol-O-methyltransferase (COMT) Val158Met increases mesolimbic dopamine s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Schizophr Bull
Prif Awduron: Debost, Jean-Christophe, Grove, Jakob, Petersen, Liselotte, Mors, Ole, Hougaard, David, Børglum, Anders, Mortensen, Preben
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Abstracts
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475474/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.049
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