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3.4 GABA Interneuron Dysfunction and the Onset of Psychosis

Background: Some animal models propose that the onset of psychosis involves dysfunction in GABAergic interneurons, leading to excessive cortical glutamatergic activity, which then drives subcortical dopamine activity. Recent neuroimaging studies in people at ultra high risk (UHR) for psychosis have...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: McGuire, Philip, Allen, Paul, Howes, Oliver, Bonoldi, Ilaria, Grace, Anthony, Simsek, Fatma, Horder, Jamie, Stone, James, Modinos, Gemma, Fusar-Poli, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475448/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.010
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