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60.4 Multimodal Evidence of GABAergic Circuit Dysfunction in People at Clinical High Risk of Psychosis

Background: Preclinical and neuropathological research in psychosis suggest that prefrontal and hippocampal GABAergic deficits in fast-spiking, parvalbumin-positive interneurons play a central role in the development of the elevations in striatal dopamine function typically observed in psychosis. Th...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Modinos, Gemma, Simsek, Fatma, Horder, Jamie, Bossong, Matthijs, Samson, Carly, Azis, Matilda, Quinn, Beverly, Bonoldi, Ilaria, Howes, Oliver, Stone, James, Allen, Paul, McGuire, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475545/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.091
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