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The HECT family ubiquitin ligase EEL-1 regulates neuronal function and development
Genetic changes in the HECT ubiquitin ligase HUWE1 are associated with intellectual disability, but it remains unknown whether HUWE1 functions in post-mitotic neurons to affect circuit function. Using genetics, pharmacology and electrophysiology, we show that EEL-1, the HUWE1 ortholog in C. elegans,...
Tallennettuna:
| Julkaisussa: | Cell Rep |
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| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475272/ https://ncbi.nlm.nih.gov/pubmed/28445732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.04.003 |
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