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LGG-13. SYNERGISTIC TREATMENT FOR PEDIATRIC LOW GRADE GLIOMA WITH THE DUAL MTORC1/2 INHIBITOR TAK-228 AND MEK INHIBITOR TRAMETINIB
Pediatric low-grade glioma (PLGG) is one of the most common childhood tumors. If the tumor is located in a brain region that is not accessible for surgical resection, additional therapies are needed. Recent studies highlighted the important role of mTORC and MEK-activation in PLGG. The dual mTORC1/2...
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| Gepubliceerd in: | Neuro Oncol |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475204/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.146 |
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